GLP-1/Exendin-4 induces β-cell proliferation via the epidermal growth factor receptor

Exendin-4 is a long acting glucagon-like peptide 1 (GLP-1) analogue that is an agonist for the GLP-1 receptor, a G-protein coupled receptor (GPCR). Exendin-4 is used to clinically improve glucose tolerance in diabetic patients due to its ability to enhance insulin secretion. In rodents, and possibly...

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Vydáno v:Sci Rep
Hlavní autoři: Fusco, Joseph, Xiao, Xiangwei, Prasadan, Krishna, Sheng, Qingfeng, Chen, Congde, Ming, Yung-Ching, Gittes, George
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567347/
https://ncbi.nlm.nih.gov/pubmed/28831150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09898-4
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