Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats. DES treatment acutely reduced serum LH levels, followed by...

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Publié dans:Sci Rep
Auteurs principaux: Imamichi, Yoshitaka, Sekiguchi, Toshio, Kitano, Takeshi, Kajitani, Takashi, Okada, Reiko, Inaoka, Yoshihiko, Miyamoto, Kaoru, Uwada, Junsuke, Takahashi, Satoru, Nemoto, Takahiro, Mano, Asuka, Khan, Md Rafiqul Islam, Islam, Md Tariqul, Yuhki, Koh-ichi, Kashiwagi, Hitoshi, Ushikubi, Fumitaka, Suzuki, Nobuo, Taniguchi, Takanobu, Yazawa, Takashi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567288/
https://ncbi.nlm.nih.gov/pubmed/28827713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08780-7
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