Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats. DES treatment acutely reduced serum LH levels, followed by...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Imamichi, Yoshitaka, Sekiguchi, Toshio, Kitano, Takeshi, Kajitani, Takashi, Okada, Reiko, Inaoka, Yoshihiko, Miyamoto, Kaoru, Uwada, Junsuke, Takahashi, Satoru, Nemoto, Takahiro, Mano, Asuka, Khan, Md Rafiqul Islam, Islam, Md Tariqul, Yuhki, Koh-ichi, Kashiwagi, Hitoshi, Ushikubi, Fumitaka, Suzuki, Nobuo, Taniguchi, Takanobu, Yazawa, Takashi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567288/
https://ncbi.nlm.nih.gov/pubmed/28827713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08780-7
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