Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats. DES treatment acutely reduced serum LH levels, followed by...

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Publicado no:Sci Rep
Main Authors: Imamichi, Yoshitaka, Sekiguchi, Toshio, Kitano, Takeshi, Kajitani, Takashi, Okada, Reiko, Inaoka, Yoshihiko, Miyamoto, Kaoru, Uwada, Junsuke, Takahashi, Satoru, Nemoto, Takahiro, Mano, Asuka, Khan, Md Rafiqul Islam, Islam, Md Tariqul, Yuhki, Koh-ichi, Kashiwagi, Hitoshi, Ushikubi, Fumitaka, Suzuki, Nobuo, Taniguchi, Takanobu, Yazawa, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567288/
https://ncbi.nlm.nih.gov/pubmed/28827713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08780-7
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