Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation

After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation. Thus, we tes...

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Publicat a:Sci Rep
Autors principals: Zebrowski, David C., Jensen, Charlotte H., Becker, Robert, Ferrazzi, Fulvia, Baun, Christina, Hvidsten, Svend, Sheikh, Søren P., Polizzotti, Brian D., Andersen, Ditte C., Engel, Felix B.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567176/
https://ncbi.nlm.nih.gov/pubmed/28827644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08947-2
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