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Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation

After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation. Thus, we tes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zebrowski, David C., Jensen, Charlotte H., Becker, Robert, Ferrazzi, Fulvia, Baun, Christina, Hvidsten, Svend, Sheikh, Søren P., Polizzotti, Brian D., Andersen, Ditte C., Engel, Felix B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567176/
https://ncbi.nlm.nih.gov/pubmed/28827644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08947-2
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