Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation

After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation. Thus, we tes...

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Published in:Sci Rep
Main Authors: Zebrowski, David C., Jensen, Charlotte H., Becker, Robert, Ferrazzi, Fulvia, Baun, Christina, Hvidsten, Svend, Sheikh, Søren P., Polizzotti, Brian D., Andersen, Ditte C., Engel, Felix B.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567176/
https://ncbi.nlm.nih.gov/pubmed/28827644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08947-2
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