Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity

Live-cell microscopy has highlighted that transcription factors bind transiently to chromatin but it is not clear if the duration of these binding interactions can be modulated in response to an activation stimulus, and if such modulation can be controlled by post-translational modifications of the...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Loffreda, Alessia, Jacchetti, Emanuela, Antunes, Sofia, Rainone, Paolo, Daniele, Tiziana, Morisaki, Tatsuya, Bianchi, Marco E., Tacchetti, Carlo, Mazza, Davide
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567047/
https://ncbi.nlm.nih.gov/pubmed/28827596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00398-7
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