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Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity
Live-cell microscopy has highlighted that transcription factors bind transiently to chromatin but it is not clear if the duration of these binding interactions can be modulated in response to an activation stimulus, and if such modulation can be controlled by post-translational modifications of the...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567047/ https://ncbi.nlm.nih.gov/pubmed/28827596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00398-7 |
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