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The needle and the haystack: single molecule tracking to probe the transcription factor search in eukaryotes

Transcription factors (TFs) regulate transcription of their target genes by identifying and binding to regulatory regions of the genome among billions of potential non-specific decoy sites, a task that is often presented as a ‘needle in the haystack’ challenge. The TF search process is now well unde...

詳細記述

保存先:
書誌詳細
出版年:Biochem Soc Trans
主要な著者: Mazzocca, Matteo, Fillot, Tom, Loffreda, Alessia, Gnani, Daniela, Mazza, Davide
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286828/
https://ncbi.nlm.nih.gov/pubmed/34003257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200709
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