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p53 Oligomerization Is Essential for Its C-terminal Lysine Acetylation

Acetylation of multiple lysine residues in the p53 plays critical roles in the protein stability and transcriptional activity of p53. To better understand how p53 acetylation is regulated, we generated a number of p53 mutants and examined acetylation of each mutant in transfected cells. We found tha...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Itahana, Yoko, Ke, Hengming, Zhang, Yanping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643511/
https://ncbi.nlm.nih.gov/pubmed/19106109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805696200
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