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Cellular requirements for iron–sulfur cluster insertion into the antiviral radical SAM protein viperin
Viperin (RSAD2) is an interferon-stimulated antiviral protein that belongs to the radical S-adenosylmethionine (SAM) enzyme family. Viperin's iron–sulfur (Fe/S) cluster is critical for its antiviral activity against many different viruses. CIA1 (CIAO1), an essential component of the cytosolic i...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5566539/ https://ncbi.nlm.nih.gov/pubmed/28615450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780122 |
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