Cellular requirements for iron–sulfur cluster insertion into the antiviral radical SAM protein viperin

Viperin (RSAD2) is an interferon-stimulated antiviral protein that belongs to the radical S-adenosylmethionine (SAM) enzyme family. Viperin's iron–sulfur (Fe/S) cluster is critical for its antiviral activity against many different viruses. CIA1 (CIAO1), an essential component of the cytosolic i...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Upadhyay, Arunkumar S., Stehling, Oliver, Panayiotou, Christakis, Rösser, Ralf, Lill, Roland, Överby, Anna K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566539/
https://ncbi.nlm.nih.gov/pubmed/28615450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780122
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