Platelets reduce anoikis and promote metastasis by activating YAP1 signaling

Thrombocytosis is present in more than 30% of patients with solid malignancies and correlates with worsened patient survival. Tumor cell interaction with various cellular components of the tumor microenvironment including platelets is crucial for tumor growth and metastasis. Although it is known tha...

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Publicado no:Nat Commun
Main Authors: Haemmerle, Monika, Taylor, Morgan L., Gutschner, Tony, Pradeep, Sunila, Cho, Min Soon, Sheng, Jianting, Lyons, Yasmin M., Nagaraja, Archana S., Dood, Robert L., Wen, Yunfei, Mangala, Lingegowda S., Hansen, Jean M., Rupaimoole, Rajesha, Gharpure, Kshipra M., Rodriguez-Aguayo, Cristian, Yim, Sun Young, Lee, Ju-Seog, Ivan, Cristina, Hu, Wei, Lopez-Berestein, Gabriel, Wong, Stephen T., Karlan, Beth Y., Levine, Douglas A., Liu, Jinsong, Afshar-Kharghan, Vahid, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566477/
https://ncbi.nlm.nih.gov/pubmed/28827520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00411-z
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