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Interaction of BiP with newly synthesized immunoglobulin light chain molecules: cycles of sequential binding and release.

Here we show that not only transport defective but all immunoglobulin light chains interact with BiP. Association of BiP with its ligand takes place during or shortly after translation of the light chains. The biological half life of the BiP-light chain complex depends on the fate of the light chain...

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Détails bibliographiques
Auteurs principaux: Knittler, M R, Haas, I G
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC556606/
https://ncbi.nlm.nih.gov/pubmed/1563355
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