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Interaction of BiP with newly synthesized immunoglobulin light chain molecules: cycles of sequential binding and release.

Here we show that not only transport defective but all immunoglobulin light chains interact with BiP. Association of BiP with its ligand takes place during or shortly after translation of the light chains. The biological half life of the BiP-light chain complex depends on the fate of the light chain...

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Detalles Bibliográficos
Main Authors: Knittler, M R, Haas, I G
Formato: Artigo
Idioma:Inglês
Publicado: 1992
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC556606/
https://ncbi.nlm.nih.gov/pubmed/1563355
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