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The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane

All enveloped viruses, including herpesviruses, must fuse their envelope with the host membrane to deliver their genomes into target cells, making this essential step subject to interference by antibodies and drugs. Viral fusion is mediated by a viral surface protein that transits from an initial pr...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Fontana, Juan, Atanasiu, Doina, Saw, Wan Ting, Gallagher, John R., Cox, Reagan G., Whitbeck, J. Charles, Brown, Lauren M., Eisenberg, Roselyn J., Cohen, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565971/
https://ncbi.nlm.nih.gov/pubmed/28830949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01268-17
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