Llwytho...

Early Genetic Restoration of Lubricin Expression in Trangenic Mice Mitigates Chondrocyte Peroxynitrite Release and Caspase-3 Activation

OBJECTIVE: This study investigated the ability of endogenous lubricin secretion to restore joint health following a brief < 21 day, postnatal lubricin-null state, in a C57BL/6J Prg4 gene trap mouse under the control of cre-recombinase. Previously we showed that re-expression of lubricin at 21 day...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Osteoarthritis Cartilage
Prif Awduron: Larson, Katherine M., Zhang, Ling, Badger, Gary J., Jay, Gregory D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565702/
https://ncbi.nlm.nih.gov/pubmed/28579418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2017.05.012
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