Lubricin restoration in a mouse model of congenital deficiency

OBJECTIVE: Congenital deficiency of the principal boundary lubricant in cartilage (lubricin, encoded by the gene PRG4) increases joint friction and causes progressive joint failure. This study was undertaken to determine whether restoring lubricin expression would prevent, delay, or reverse the dise...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Hill, Adele, Waller, Kimberly A., Cui, Yajun, Allen, Justin M., Smits, Patrick, Zhang, Ling X., Ayturk, Ugur M., Hann, Steven, Lessard, Samantha G., Zurakowski, David, Warman, Matthew L., Jay, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626303/
https://ncbi.nlm.nih.gov/pubmed/26216721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39276
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