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Lubricin restoration in a mouse model of congenital deficiency
OBJECTIVE: Congenital deficiency of the principal boundary lubricant in cartilage (lubricin, encoded by the gene PRG4) increases joint friction and causes progressive joint failure. This study was undertaken to determine whether restoring lubricin expression would prevent, delay, or reverse the dise...
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| 出版年: | Arthritis Rheumatol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626303/ https://ncbi.nlm.nih.gov/pubmed/26216721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39276 |
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