Lubricin restoration in a mouse model of congenital deficiency

OBJECTIVE: Congenital deficiency of the principal boundary lubricant in cartilage (lubricin, encoded by the gene PRG4) increases joint friction and causes progressive joint failure. This study was undertaken to determine whether restoring lubricin expression would prevent, delay, or reverse the dise...

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Bibliografske podrobnosti
izdano v:Arthritis Rheumatol
Main Authors: Hill, Adele, Waller, Kimberly A., Cui, Yajun, Allen, Justin M., Smits, Patrick, Zhang, Ling X., Ayturk, Ugur M., Hann, Steven, Lessard, Samantha G., Zurakowski, David, Warman, Matthew L., Jay, Gregory D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626303/
https://ncbi.nlm.nih.gov/pubmed/26216721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39276
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