Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies

The recent outbreak of Zika virus (ZIKV) has been associated with fetal abnormalities and neurological complications, prompting global concern. Here we present a mathematical analysis of the within-host dynamics of plasma ZIKV burden in a nonhuman primate model, allowing for characterization of the...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Best, Katharine, Guedj, Jeremie, Madelain, Vincent, de Lamballerie, Xavier, Lim, So-Yon, Osuna, Christa E., Whitney, James B., Perelson, Alan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565429/
https://ncbi.nlm.nih.gov/pubmed/28765371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704011114
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