A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade

Neural injury triggers swift responses from glia, including glial migration and phagocytic clearance of damaged neurons. The transcriptional programs governing these complex innate glial immune responses are still unclear. Here, we describe a novel injury assay in adult Drosophila that elicits wides...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Purice, Maria D, Ray, Arpita, Münzel, Eva Jolanda, Pope, Bernard J, Park, Daniel J, Speese, Sean D, Logan, Mary A
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565368/
https://ncbi.nlm.nih.gov/pubmed/28825401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23611
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge