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Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity
Advanced age is the greatest risk factor for neurodegenerative disorders, but the mechanisms that render the senescent brain vulnerable to disease are unclear. Glial immune responses provide neuroprotection in a variety of contexts. Thus, we explored how glial responses to neurodegeneration are alte...
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Publicado no: | Nat Commun |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034330/ https://ncbi.nlm.nih.gov/pubmed/27647497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12871 |
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