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Insulin-like signaling promotes glial phagocytic clearance of degenerating axons through regulation of Draper

Neuronal injury triggers robust responses from glial cells, including altered gene expression and enhanced phagocytic activity to ensure prompt removal of damaged neurons. The molecular underpinnings of glial responses to trauma remain unclear. Here, we find that the evolutionarily conserved Insulin...

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Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Musashe, Derek T., Purice, Maria D., Speese, Sean D., Doherty, Johnna, Logan, Mary A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066579/
https://ncbi.nlm.nih.gov/pubmed/27498858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.022
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