Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry

Fibrosis is a hallmark of many cardiovascular diseases and is associated with the exacerbated secretion and deposition of the extracellular matrix (ECM). Using proteomics, we have previously identified more than 150 ECM and ECM-associated proteins in cardiovascular tissues. Notably, many ECM protein...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Barallobre-Barreiro, Javier, Baig, Ferheen, Fava, Marika, Yin, Xiaoke, Mayr, Manuel
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2017
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565024/
https://ncbi.nlm.nih.gov/pubmed/28518125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55674
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