Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome.

In humans, trisomy 21 results in a specific phenotype known as Down syndrome (DS). The mechanism by which an extra copy of normal genes leads to the DS phenotype is unknown. Most studies in DS and other aneuploid organisms have shown that gene dose is proportional to gene expression. To date, most g...

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Detaylı Bibliyografya
Asıl Yazarlar: Holtzman, D M, Bayney, R M, Li, Y W, Khosrovi, H, Berger, C N, Epstein, C J, Mobley, W C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1992
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC556494/
https://ncbi.nlm.nih.gov/pubmed/1371464
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