The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells

Galectin-3 is a galectin with a unique flexible N-terminal tail (NT) connected to the conserved carbohydrate recognition domain (CRD). Galectin-3 is associated with tumor immune tolerance and exhibits an ability to induce T cell apoptosis. We used Jurkat, Jurkat E6-1 and CEM T-cell lines and human p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xue, Huiting, Liu, Lu, Zhao, Zihan, Zhang, Zhongyu, Guan, Yuan, Cheng, Hairong, Zhou, Yifa, Tai, Guihua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564810/
https://ncbi.nlm.nih.gov/pubmed/28548942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17760
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