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Crystallization of Galectin-8 Linker Reveals Intricate Relationship between the N-terminal Tail and the Linker

Galectin-8 (Gal-8) plays a significant role in normal immunological function as well as in cancer. This lectin contains two carbohydrate recognition domains (CRD) connected by a peptide linker. The N-terminal CRD determines ligand binding specificity, whereas the linker has been proposed to regulate...

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Bibliografische gegevens
Hoofdauteurs: Yunlong Si, Yue Wang, Jin Gao, Chenyang Song, Shiqiong Feng, Yifa Zhou, Guihua Tai, Jiyong Su
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2016-12-01
Reeks:International Journal of Molecular Sciences
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Online toegang:http://www.mdpi.com/1422-0067/17/12/2088
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