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Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer
Sestrin 2 is a conserved antioxidant protein that reduces reactive oxygen species (ROS) and inhibits mammalian target of rapamycin complex 1 (mTORC1). We previously showed that sestrin 2 is abnormally decreased in colorectal cancer (CRC). To elucidate the molecular mechanism behind the potential con...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564770/ https://ncbi.nlm.nih.gov/pubmed/28525387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17595 |
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