Mathematical modeling for Phase I cancer trials: A study of metronomic vinorelbine for advanced non-small cell lung cancer (NSCLC) and mesothelioma patients

INTRODUCTION: Using mathematical modelling allows to select a treatment's regimen across infinite possibilities. Here, we report the phase I assessment of a new schedule for metronomic vinorelbine in treating refractory advanced NSCLC and mesothelioma patients. RESULTS: Overall, 13 patients wer...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Barlesi, Fabrice, Imbs, Diane-Charlotte, Tomasini, Pascale, Greillier, Laurent, Galloux, Melissa, Testot-Ferry, Albane, Garcia, Mélanie, Elharrar, Xavier, Pelletier, Annick, André, Nicolas, Mascaux, Céline, Lacarelle, Bruno, Cheikh, Raouf El, Serre, Raphaël, Ciccolini, Joseph, Barbolosi, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564552/
https://ncbi.nlm.nih.gov/pubmed/28525370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17562
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