Revisiting Bevacizumab + Cytotoxics Scheduling Using Mathematical Modeling: Proof of Concept Study in Experimental Non‐Small Cell Lung Carcinoma

Concomitant administration of bevacizumab and pemetrexed‐cisplatin is a common treatment for advanced nonsquamous non‐small cell lung cancer (NSCLC). Vascular normalization following bevacizumab administration may transiently enhance drug delivery, suggesting improved efficacy with sequential admini...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Imbs, Diane‐Charlotte, El Cheikh, Raouf, Boyer, Arnaud, Ciccolini, Joseph, Mascaux, Céline, Lacarelle, Bruno, Barlesi, Fabrice, Barbolosi, Dominique, Benzekry, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784740/
https://ncbi.nlm.nih.gov/pubmed/29218795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12265
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