A phase Ia/Ib clinical trial of metronomic chemotherapy based on a mathematical model of oral vinorelbine in metastatic non-small cell lung cancer and malignant pleural mesothelioma: rationale and study protocol

BACKGROUND: Metronomic oral vinorelbine is effective in metastatic NSCLC and malignant pleural mesothelioma, but all the studies published thus far were based upon a variety of empirical and possibly suboptimal schedules, with inconsistent results. Mathematical modelling showed by simulation that a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Cancer
Egile Nagusiak: Elharrar, Xavier, Barbolosi, Dominique, Ciccolini, Joseph, Meille, Christophe, Faivre, Christian, Lacarelle, Bruno, André, Nicolas, Barlesi, Fabrice
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Study Protocol
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837593/
https://ncbi.nlm.nih.gov/pubmed/27094927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2308-z
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