Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer

PR domain zinc finger protein 14 (PRDM14) maintains stemness in embryonic stem cells via epigenetic mechanisms. Although PRDM14 is elevated in several cancers, it is unclear if and how PRDM14 confers stem cell-like properties and epigenetic changes to cancer cells. Here, we examined the phenotypic c...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Taniguchi, Hiroaki, Hoshino, Daisuke, Moriya, Chiharu, Zembutsu, Hitoshi, Nishiyama, Nobuhiro, Yamamoto, Hiroyuki, Kataoka, Kazunori, Imai, Kohzoh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564528/
https://ncbi.nlm.nih.gov/pubmed/28423353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16776
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller