Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer

PR domain zinc finger protein 14 (PRDM14) maintains stemness in embryonic stem cells via epigenetic mechanisms. Although PRDM14 is elevated in several cancers, it is unclear if and how PRDM14 confers stem cell-like properties and epigenetic changes to cancer cells. Here, we examined the phenotypic c...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Taniguchi, Hiroaki, Hoshino, Daisuke, Moriya, Chiharu, Zembutsu, Hitoshi, Nishiyama, Nobuhiro, Yamamoto, Hiroyuki, Kataoka, Kazunori, Imai, Kohzoh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564528/
https://ncbi.nlm.nih.gov/pubmed/28423353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16776
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