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Dynamics of RNA polymerase II pausing and bivalent histone H3 methylation during neuronal differentiation in brain development

During cellular differentiation, genes important for differentiation are expected to be silent in stem/progenitor cells yet can be readily activated. RNA polymerase II (Pol II) pausing and bivalent chromatin marks are two paradigms suited for establishing such a poised state of gene expression, howe...

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Publicat a:Cell Rep
Autors principals: Liu, Jiancheng, Wu, Xiwei, Zhang, Heying, Pfeifer, Gerd P., Lu, Qiang
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564459/
https://ncbi.nlm.nih.gov/pubmed/28793256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.046
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