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Dynamics of promoter bivalency and RNAP II pausing in mouse stem and differentiated cells

BACKGROUND: Mammalian embryonic stem cells display a unique epigenetic and transcriptional state to facilitate pluripotency by maintaining lineage-specification genes in a poised state. Two epigenetic and transcription processes involved in maintaining poised state are bivalent chromatin, characteri...

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Detalhes bibliográficos
Publicado no:BMC Dev Biol
Main Authors: Mantsoki, Anna, Devailly, Guillaume, Joshi, Anagha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819258/
https://ncbi.nlm.nih.gov/pubmed/29458328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-018-0163-7
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