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CpG island erosion, polycomb occupancy and sequence motif enrichment at bivalent promoters in mammalian embryonic stem cells

In embryonic stem (ES) cells, developmental regulators have a characteristic bivalent chromatin signature marked by simultaneous presence of both activation (H3K4me3) and repression (H3K27me3) signals and are thought to be in a ‘poised’ state for subsequent activation or silencing during differentia...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mantsoki, Anna, Devailly, Guillaume, Joshi, Anagha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652170/
https://ncbi.nlm.nih.gov/pubmed/26582124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16791
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