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PhredEM: A Phred-Score-Informed Genotype-Calling Approach for Next-Generation Sequencing Studies

A fundamental challenge in analyzing next-generation sequencing data is to determine an individual’s genotype accurately, as the accuracy of the inferred genotype is essential to downstream analyses. Correctly estimating the base-calling error rate is critical to accurate genotype calls. Phred score...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Liao, Peizhou, Satten, Glen A., Hu, Yi-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564424/
https://ncbi.nlm.nih.gov/pubmed/28560825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22048
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