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Utilization of Optimal Study Design for Maternal and Fetal Sheep Propofol Pharmacokinetics Study: A Preliminary Study

Multiple blood samples are generally required for measurement of pharmacokinetic (PK) parameters. D-optimal design is a popular and frequently used approach for determination of sampling time points in order to minimize the number of samples, while optimizing the estimation of PK parameters. Optimal...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Clin Pharmacol
Egile Nagusiak: Sherwin, Catherine M. T., Ngamprasertwong, Pornswan, Sadhasivam, Senthilkumar, Vinks, Alexander A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564389/
https://ncbi.nlm.nih.gov/pubmed/24219004
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