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Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen via Rh(III)-Catalyzed C-H Functionalization of Alkenyl Azoles

The first syntheses of privileged [5,6]-bicyclic heterocycles with ring-junction nitrogens by transition-metal-catalyzed C-H functionalization of C-alkenyl azoles is disclosed. Several reactions are applied to alkenyl imidazoles, pyrazoles and triazoles to provide products with nitrogen incorporated...

Ausführliche Beschreibung

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Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Halskov, Kim Søholm, Roth, Howard S., Ellman, Jonathan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564303/
https://ncbi.nlm.nih.gov/pubmed/28586164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703967
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