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Biogenic Aldehydes as Therapeutic Targets for Cardiovascular Disease

Aldehydes are continuously formed in biological systems through enzyme-dependent and spontaneous oxidation of lipids, glucose, and primary amines. These highly reactive, biogenic electrophiles can become toxic via covalent modification of proteins, lipids and DNA. Thus, agents that scavenge aldehyde...

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Vydáno v:Curr Opin Pharmacol
Hlavní autoři: Nelson, Margaret-Ann M, Baba, Shahid P, Andersonc, Ethan J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563970/
https://ncbi.nlm.nih.gov/pubmed/28528297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2017.04.004
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