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Biogenic Aldehydes as Therapeutic Targets for Cardiovascular Disease

Aldehydes are continuously formed in biological systems through enzyme-dependent and spontaneous oxidation of lipids, glucose, and primary amines. These highly reactive, biogenic electrophiles can become toxic via covalent modification of proteins, lipids and DNA. Thus, agents that scavenge aldehyde...

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Detalhes bibliográficos
Publicado no:Curr Opin Pharmacol
Main Authors: Nelson, Margaret-Ann M, Baba, Shahid P, Andersonc, Ethan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563970/
https://ncbi.nlm.nih.gov/pubmed/28528297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2017.04.004
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