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GNAS Mutations in Fibrous Dysplasia: A Comparative Study of Standard Sequencing and Locked Nucleic Acid PCR Sequencing on Decalcified and Non-Decalcified Formalin Fixed Paraffin Embedded Tissues
It is well-known that fibrous dysplasia is characterized by the presence of activating mutations involving G-nucleotide binding protein alpha sub unit (GNAS) involving codon R201 and rarely codon 227 with a mutation frequency between 45–93%. Herein, we investigate the sensitivity of detection of GNA...
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| Publicado en: | Appl Immunohistochem Mol Morphol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563825/ https://ncbi.nlm.nih.gov/pubmed/26574629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0000000000000242 |
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