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Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates
Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial ‘silver bullet’ for controlling invasive alien species. Homing-based drives comprise an endonuclease and a guide RNA (gRNA) that are replicated during mei...
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| Veröffentlicht in: | Proc Biol Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563802/ https://ncbi.nlm.nih.gov/pubmed/28794219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2017.0799 |
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