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Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates

Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial ‘silver bullet’ for controlling invasive alien species. Homing-based drives comprise an endonuclease and a guide RNA (gRNA) that are replicated during mei...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Prowse, Thomas A. A., Cassey, Phillip, Ross, Joshua V., Pfitzner, Chandran, Wittmann, Talia A., Thomas, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563802/
https://ncbi.nlm.nih.gov/pubmed/28794219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2017.0799
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