Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates

Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial ‘silver bullet’ for controlling invasive alien species. Homing-based drives comprise an endonuclease and a guide RNA (gRNA) that are replicated during mei...

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Dades bibliogràfiques
Publicat a:Proc Biol Sci
Autors principals: Prowse, Thomas A. A., Cassey, Phillip, Ross, Joshua V., Pfitzner, Chandran, Wittmann, Talia A., Thomas, Paul
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2017
Matèries:
Ecology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563802/
https://ncbi.nlm.nih.gov/pubmed/28794219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2017.0799
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