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Hypoxia-controlled matrix metalloproteinase-9 hyperexpression promotes behavioral recovery after ischemia

Matrix metalloproteinase-9 (MMP-9) plays a beneficial role in the sub-acute phase after ischemic stroke. However, unrestrained MMP-9 may disrupt the blood-brain barrier (BBB), which has limited its use for the treatment of brain ischemia. In the present study, we constructed lentivirus mediated hypo...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Cai, Hongxia, Mu, Zhihao, Jiang, Zhen, Wang, Yongting, Yang, Guo-Yuan, Zhang, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563676/
https://ncbi.nlm.nih.gov/pubmed/25975730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-015-1533-1
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