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Matrix Metalloproteinase-9 Gene Knock-out Protects the Immature Brain after Cerebral Hypoxia–Ischemia

Inhibition of matrix metalloproteinase-9 (MMP-9) protects the adult brain after cerebral ischemia. However, the role of MMP-9 in the immature brain after hypoxia–ischemia (HI) is unknown. We exposed MMP-9((−/−)) [MMP-9 knock-out (KO)] and wild-type (WT) mice to HI on postnatal day 9. HI was induced...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Svedin, Pernilla, Hagberg, Henrik, Sävman, Karin, Zhu, Changlian, Mallard, Carina
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673738/
https://ncbi.nlm.nih.gov/pubmed/17301159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4391-06.2007
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