Increased Resistance to Intradermal Francisella tularensis LVS Infection by Inactivation of the Sts Phosphatases

The Suppressor of TCR signaling proteins (Sts-1 and Sts-2) are two homologous phosphatases that negatively regulate signaling pathways in a number of hematopoietic lineages, including T lymphocytes. Mice lacking Sts expression are characterized by enhanced T cell responses. Additionally, a recent st...

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Vydáno v:Infect Immun
Hlavní autoři: Parashar, Kaustubh, Kopping, Erik, Frank, David, Sampath, Vinaya, Thanassi, David G., Carpino, Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563576/
https://ncbi.nlm.nih.gov/pubmed/28630061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00406-17
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