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Francisella tularensis LVS Induction of Prostaglandin Biosynthesis by Infected Macrophages Requires Specific Host Phospholipases and Lipid Phosphatases

Francisella tularensis induces the synthesis of prostaglandin E(2) (PGE(2)) by infected macrophages to alter host immune responses, thus providing a survival advantage to the bacterium. We previously demonstrated that PGE(2) synthesis by F. tularensis-infected macrophages requires cytosolic phosphol...

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Detalhes bibliográficos
Main Authors: Navratil, Aaron R., Brummett, Ashley M., Bryan, Joshua D., Woolard, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136233/
https://ncbi.nlm.nih.gov/pubmed/24866789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02060-14
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