3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders

Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement and provide new opportunities to explore disease pathogenesi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomed Sci
Main Authors: Lee, Chun-Ting, Bendriem, Raphael M., Wu, Wells W., Shen, Rong-Fong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563385/
https://ncbi.nlm.nih.gov/pubmed/28822354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0362-8
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