Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

Human organoid systems recapitulate in vivo organ architecture, yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible method to derive multi-cellular human liver organoids comp...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cell Metab
Hoofdauteurs: Ouchi, Rie, Togo, Shodai, Kimura, Masaki, Shinozawa, Tadahiro, Koido, Masaru, Koike, Hiroyuki, Thompson, Wendy, Karns, Rebekah, Mayhew, Christopher, McGrath, Patrick S., McCauley, Heather A., Zhang, Ran-Ran, Lewis, Kyle, Hakozaki, Shoyo, Ferguson, Autumn, Saiki, Norikazu, Yoneyama, Yosuke, Takeuchi, Ichiro, Mabuchi, Yo, Akazawa, Chihiro, Yoshikawa, Hiroshi Y., Wells, James M., Takebe, Takanori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687537/
https://ncbi.nlm.nih.gov/pubmed/31155493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.05.007
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items