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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
Human organoid systems recapitulate in vivo organ architecture, yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible method to derive multi-cellular human liver organoids comp...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687537/ https://ncbi.nlm.nih.gov/pubmed/31155493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.05.007 |
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