Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

Human organoid systems recapitulate in vivo organ architecture, yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent stem cell lines, we developed a reproducible method to derive multi-cellular human liver organoids comp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Metab
Autors principals: Ouchi, Rie, Togo, Shodai, Kimura, Masaki, Shinozawa, Tadahiro, Koido, Masaru, Koike, Hiroyuki, Thompson, Wendy, Karns, Rebekah, Mayhew, Christopher, McGrath, Patrick S., McCauley, Heather A., Zhang, Ran-Ran, Lewis, Kyle, Hakozaki, Shoyo, Ferguson, Autumn, Saiki, Norikazu, Yoneyama, Yosuke, Takeuchi, Ichiro, Mabuchi, Yo, Akazawa, Chihiro, Yoshikawa, Hiroshi Y., Wells, James M., Takebe, Takanori
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687537/
https://ncbi.nlm.nih.gov/pubmed/31155493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.05.007
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars