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3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders

Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement and provide new opportunities to explore disease pathogenesi...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Lee, Chun-Ting, Bendriem, Raphael M., Wu, Wells W., Shen, Rong-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563385/
https://ncbi.nlm.nih.gov/pubmed/28822354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0362-8
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